Issue 3/2002

Issue: 3/2002 Author: G. Kirilov, B. Lozanov, Clinical Center of Endocrinology and Gerontology Medical University – Sofia   Abstract:  Improvements in sensitivity and specificity of biochemical thyroid tests account for considerable progress in clinical strategies for diagnosing and treating thyroid disorders. This is a survey paper designed to present an updated overview of the potentials and shortcomings […]

Issue: 3/2002 Author: A.Tomova, O. Koseva, Ph. Kumanov, Clinical Center of Endocrinology and Gerontology Medical University-Sofia   Abstract:    This is a survey paper outlining the endocrine role of gonadal inhibin A and inhibin В in the human. McCullagh in 1932 reported that an aqueous testicular extract interferes with the formation of "castration cells" in the rat […]

Issue: 3/2002   Author: M. Yaneva, S. Zacharieva, Clinical Center of Endocrinology and Gerontology Medical University-Sofia   Abstract:    Cortisol secretion mechanisms in the so-called primary adrenal Cushing's syndrome where ACTH level is lowered are unknown, and so far presumed to be due to an "autonomous" secretion. Nowadays, in vitro and in vivo studies by a number […]

Issue: 3/2002 Author: Z. Abadjieva, G. Kirilov, Ph. Kumanov, Clinical Center of Endocrinology and Gerontology Medical University – Sofia   Abstract:    It is the purpose of this survey paper to gain better insight into free testosterone determination and evaluation methods. A fraction of total testosterone circulates in the plasma, specifically bound to the sex hormone-binding globulin (SHBG), another […]

Issue: 3/2002 Author: S. Vladeva, Clinic of Endocrinology, HigerMedical Institute-Plovdiv   Abstract:    Over the past few years, a number of experimental and clinical studies contribute greatly to gain better insight into the effect exerted by microelements on the human organism. As shown by the results, they have an essential practical bearing on a number of biochemical processes. […]

Issue: 3/2002 Author: Zh. Boneva, VI. Christov* Department of Endocrinology, Hospital of the Ministry of Internal Affairs – Sofia * Clinic of Endocrinology, Alexandrov's Hospital – Sofia   Abstract:    Effective treatment of obesity may reduce substantially the risk of overweight comorbidities, and accordingly result in mortality rate decrease. Sibutramine hydrochloride (Reductil) is a serotonin (5-HT) […]