Issue 2/2003

Neuroendocrine Bases of the Metabolic Syndrome

Author: S. Zacharieva, M. Yaneva, Clinical Center of Endocrinology and Gerontology Medical University – Sofia Abstract: A series of recent experimental and clinical data show the existence of neuroendocrine disturbances in metabolic syndrome. First and foremost, the review considers the disorders of hypothalamic-pituitary-adrenocortical axis. The observed status of "functional hypercortisolism" in metabolic syndrome could play a […]


Secondary Osteoporosis

Issue: 2/2003 Author: A.-M. Borissova, Clinical Center of Endocrinology and Gerontology Medical University – Sofia Abstract: A large number of medical disorders are associated with osteoporosis and increased fracture risk. These can be organized into several categories – genetic disorders, hypogonadal states, endocrine disorders, gastrointestinal diseases, hematologic disorders, connective tissue disease, nutritional deficiencies, drugs, and a variety […]


From Renal Osteodystrophy to Senile Osteoporosis

Issue: 2/2003 Author: S. Krivoshiev, A.-M. Borissova*, Dialisis Unit, MBAL "Tzaritza Joanna" – Sofia, *Clinical Center of Endocrinology and Gerontology, Medical University – Sofia Abstract: Renal osteodystrophy affects nearly all patients with chronic renal failure. This disease needs to be recognized and treated to improve the outcome of dialisis patients. Renal osteodystrophy is a mixture of pathophysiologically different […]


Plasma, Serum and Tissue Assay of Chromogranin A in Gastroenteropancreatic Neuroendocrine Tumours

Issue: 2/2003   Author: F. Cirillo, A. Bottini, G. Lima*, E. Gnocchi**, P. Alquati, Department of General Surgery, *Department of Radiotherapy, Nuclear Medicine Division, **Department of Clinical Pathology, Istituti Ospitalieri – Cremona, Italy Abstract:  Gastroenteropancreatic neuroendocrine tumours are infrequent nosological entities. The laboratory diagnosis is linked the level of some plasma peptides and other markers, including neuron-specific […]


Serum Levels of Growth Hormone and Insulin-like Growth Factor-1 in Children with Type 1 Diabetes

Issue: 2/2003 Author: M. Archinkova, K. Koprivarova, G. Kirilov*, Z. Abadjieva*, Clinic of Diabetes, University Children's Hospital – Sofia 'Clinical Center of Endocrinology and Gerontology, Medical University – Sofia Abstract: The aim of the current work was to evaluate serum levels of insulin-like growth factor-1 (IGF-1) and growth hormone (GH) in children and adolescents with diabetes mellitus […]


Dietary Approaches for Treatment of Obesity

Issue: 2/2003 Author: Zh. Boneva, P. Popivanov*, M. Protich, M. Bojanov*, Department of Endocrinology, Hospital of Ministry of Internal affairs, Medical Institute – Sofia, *Clinic of Endocrinology, "Alexandrov's" Hospital – Sofia Abstract: Diet is one of the cornestones of a weight loss programme. The prescribed energy intake should be based on an estimate of the patient's energy requirements. For […]


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Journal of the Bulgarian Society of Endocrinology

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