Issue 2/2004

Issue: 2/2004 Author: Boika Milcheva, Maria Orbetzova Clinical Centre of Endocrinology and Gerontology Medical University-Sofia Abstract:  Adipose tissue is the body's largest reserve of fuel. Until recently, adipocytes were viewed as playing a passive role in fuel homeostasis. Today it is already known that they take active part in this process. The discovery of leptin confirmed […]

Issue: 2/2004 Author: N. Zlatareva, *S. Zaharieva, Е. Nachev   Clinic of Cardiology, University Hospital „Queen Ciovanna" – Sofia *Clinical Center of Endocrinology and Gerontology Medical University – Sofia Abstract:  Cardiovascular involvement represents the major cause of death in patients with acromegaly. The poor prognosis is due not only to systemic hypertension and coronary heart disease, […]

Issue: 2/2004 Author: P. Kamenova, D. Koev, G. Kirilov, L. Dakovska Clinical Center of Endocrinology and Gerontology Medical University – Sofia Abstract:  The „gold standard" for quantitative assessment of insulin sensitivity is the hyperinsulinaemic eugly­caemic clamp-technique. This method is physio­logical, noninvasive, reproducible and highly infor­mative, but it requires special knowledge and skills and it is difficult […]

Issue: 2/2004 Author: A. Elenkova, S. Zaharieva Clinical Center of Endocrinology and Gerontology Abstract: Gitelman's syndrome and Bartter's syndrome are primary hereditary recessive autosomal tubu-lopathies. They are characterized by hypochloremia, hypokalemia, metabolic alkalosis and hypertrophy of the juxtaglomerular complex with secondary hyperaldosteronism and normal blood pressure. They result from mutations leading to a defect of sodium reabsorption […]

Issue: 2/2004 Author: G. Kirilov1, E. Natchev1, S. Zaharieva1, L. Dakovska1, P. Doukova2, A. Alexandrov3 Clinical Center of Endocrinology, Sofia1, Department of Clinical Chemistry, Medical University, Sofia2, Institute of Biophysics, Bulgarian Academy of Science3 Abstract: The aim of the present study was to evaluate endothelin (ET) plasma levels and plasma total homocystein (tHcy) as biochemical markers of […]

Issue: 2/2004 Author: R. Nenkov1, R. Radev1, Y. Kuzmanov1, S. Kornovsky1, S. Kuzmanov1, K. Christozov2, I. Krasnaliev3 Clinic of Thoracic Surgery1, Clinic of Endocrinology 2, Clinic of Pathomorphology3 Medical Uni­versity, Varna, Bulgaria Abstract: A new technique of thyroid resection is reported. It uses an argonplasma coagulation sys­tem and is applied at the present only in […]

Issue: 2/2004 Author: G. Kirilov , A. Alexandrov* Clinical Center of Endocrinology, Medical University, Sofia * Institute of Biophysics, Bulgarian Academy of Sciences Abstract: Recent findings have been shown that the laboratory TSH reference range (0,3-4,0 mlU/L) needs to be reevaluated and reset to 0,4 to 2,5 mlU/L in order to reflect TSH levels of normal […]