Primary Disorders of Phosphate Metabolism
Issue: 1/2010 Author: Prof. Anna-Maria Borissova Abstract: The phosphate balance depends primarily upon gastrointestinal absorption and renal excretion. Several hormones and metabolic pertubations are able to modulate phosphate reabsorption by the kidney. Among these PTH, PTHrP, calcitonin, glucocorticoids and phosphate loading inhibit renal phosphate reabsorption. In contrast, IGF-1, insulin, thyroid hormone, 1,25(OH)2D and phosphate deprivation stimulate […]