Issue 1/2010

Primary Disorders of Phosphate Metabolism

Issue: 1/2010 Author: Prof. Anna-Maria Borissova Abstract:  The phosphate balance depends primarily upon gastrointestinal absorption and renal excretion. Several hormones and metabolic pertubations are able to modulate phosphate reabsorption by the kidney. Among these PTH, PTHrP, calcitonin, glucocorticoids and phosphate loading inhibit renal phosphate reabsorption. In contrast, IGF-1, insulin, thyroid hormone, 1,25(OH)2D and phosphate deprivation stimulate […]


Adypocytokines in Normal and Complicated by Gestational Diabetes Mellitus Pregnancy

Issue: 1/2010 Author: M. Boyadzhieva, I. Atanasova, Tz. Tankova, K. Todorova, V. Dimitrova, S. Zaharieva Abstract:  Human pregnancy is characterized by insulin resistance, traditionally attributed to the effects of placental hormones. Normal pregnancy – induced insulin resistance is further enhanced by pregnancy complications, associated with disturbed placental function, such as gestational diabetes mellitus (GDM). Nowadays GDM […]


The Nutrional Supplement DIALEVEL Improves Glycaemic Control in Type 2 Diabetic Patients

Issue: 1/2010 Author: D. Koev, L. Koeva Abstract:  Experimental studies proved that cinnamon (cinnamomum cassia) and its water extracts contain methylhydroxychalcone polymer (MHPC). It stmulates glucose uptake by muscles and adipocytes by means of an increased insulin sensitivity and besides, it stimulates glycogen synthesis from glucose in the liver. The net result is a decrease of […]


Prevalence of Primary Aldosteronism Among Hypertensive Patients in the Bulgarian Reference Centre for Endocrinology

Issue: 1/2010 Author: Joanna Matrozova, Sabina Zacharieva, Georgi Kirilov, Mihail Boyanov, Vladimir Hristov Abstract:  Objective. Primary aldosteronism (PA) has long been considered a rare cause of hypertension, but a higher prevalence was suggested in the last 15 years. Until now there are no data on the prevalence of PA in Bulgaria. The aim of this study […]


Evaluation of Bone Mineral Density and Sex Hormone Levels in Insulin Treated Men with Type 2 Diabetes

Issue: 1/2010 Author: Encho Enchev Abstract:  Regardless of the higher bone mineral density, patients with type 2 diabetes have increased fracture rate of upper and lower limb, ankle and hip.   AIM: Evaluation of sex hormone levels and lumbar spine bone mineral density in insulin treated men with type 2 diabetes and healthy controls.   MATERIAL […]


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Journal of the Bulgarian Society of Endocrinology

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