Syndromes of Reduced Sensitivity to Thiroid Hormone Genettic Defects in Hormone Receptors, Gell Transporters and Deiodination
Issue: 4/2010 Author: Samuel Refetoff and Alexandra M. Dumitrescu Abstract: At least six major steps are required for secreted thyroid hormone (TH) to exert its action on target tissues. Mutations interfering with three of these steps have been so far identified and are the subject of this communication. The first recognized defect, causing resistance to TH, […]