Issue 3/2011

Issue: 3/2011 Author: Boyan Lozanov Abstract: Many studies in the last years demonstrate a high co-morbidity and similar pathogenetic characteristics between Metabolic syndrome (MS) and Diabetes mellitus type 2 (DM-2) on one hand, and Chronic obstructive pulmonary disease (COPD) on the other. The frequency of each increases over the age achieving epidemic levels in the population […]

Issue: 3/2011   Author: Mihail Boyanov, Vasil Valov, Ole Henriksen, Genka Petrova Abstract: The objective of this study was to model and evaluate the consequences of an enhanced treatment of type 2 diabetes mellitus on cost, life expectancy and development of complications in the Bulgarian health care system. The extensively published and validated CORE Diabetes Model […]

Issue: 3/2011 Author: Atanaska Elenkova, Mariya Yaneva, Nicolai Genov, Zdravka Abadzhieva, Georgi Kirilov, Krasimir Kalinov, Sabina Zacharieva Abstract: Background: Macroprolactinemia is a state of hyperprolactinemia due predominantly to presence of the high-molecular form of prolactin in the circulation. Data concerning the biological activity and the site of synthesis of macroprolactin are controversial. Aim: The aim of […]

Issue: 3/2011 Author: R. Robeva, D. Tanev, Ph. Kumanov, R. Rashkov, Zl. Kolarov Abstract: Lupus erythematosus disseminatus (LED) is a systemic autoimmune disease, which affects predominantly women in reproductive age. The pronounced sexual dimorphism points to the assumption, that different levels of sex hormones could take place in the pathogenesis of the disease. Despite many investigations […]