Issue 4/2011

Issue: 4/2011 Author: B.Kanazirev, K. Hristozov, M. Bachvarova, G. Georgieva, M. Dimova Abstract: The cardiovascular signs and symptoms of thyroid disease are some of the most profound and clinically relevant findings that accompany hyperthyroidism. On the basis of the understanding of the cellular mechanisms of thyroid hormone action on the heart and cardiovascular system, it is […]

Issue: 4/2011 uthor: V. Iotova, Ch. Petrova, K. Koprivarova Abstract: Diabetes is the most prevalent chronic metabolic disease in childhood, which is increasing fast below 5 years of age. This creates a number of additional problems, the most important of which is to ensure safety with less severe hypoglycemias, without derangements of stabile good glycemic control. […]

Issue: 4/2011 Author: E. Natchev, G.Kirilov, I. Atanasova, J. Matrozova, K. Kalinov, S. Zacharieva Abstract: A high prevalence of hypertension (HTN) in acromegaly has been reported. Different mechanisms, which have not been clearly elucidated yet, participate in the pathogenesis of HTN in acromegalic patients.   Aim. To determine the prevalence of HTN in acromegalic patients; to […]

Issue: 4/2011 Author: G. Bocheva and N. Boyadjieva Abstract: The use of some opioids may affect prolactin levels. The goal of the present study is to investigate the effect of opioid agonist DAMGO [(D-Ala2, NMe-Phe4, Glyol5)-enkephalin], alone or in combination with alcohol, on prolactin secretion. The results show that DAMGO increases the plasma levels of prolactin, […]

Issue: 4/2011   Author: N. Boyadjieva and G. Bocheva Abstract: The current investigation demonstrates for the first time prenatal effects of Diazepam on beta-endorphin. The results of the experimental study show that multiple introduction of Diazepam in pregnant rats decreases plasma levels of beta-endorphin in the offspring of male rats and reduces the total number of […]