Issue 4/2014

Epigenetic and Molecular Mechanisms of Prenatal Programming of Diabetes with Obesity

Issue: 4/2014 Author: Boyadjieva, Nadka I. , Varadinova, Miroslava G. , Metodieva, Rositsa D. Department of Pharmacology and Toxicology, Medical Faculty, Medical University, Sofia   Abstract: Various factors play role in the mechanisms that underlie the development of type 2 diabetes mellitus (T2DM). It is well known that obesity is one of them. The prenatal programming […]


Characteristics of the Metabolic Syndrome in Childhood and Adolescence

Issue: 4/2014 Author: Konsulova, Petya S.1, Orbetzova, Maria M.1, Kaleva, Nartzis N.2 1 Clinic of Endocrinology and Metabolic Diseases, 2 Clinic of Children and Genetic Diseases, “Sv. Georgy” University Hospital, Plovdiv, Medical University, Plovdiv   Abstract: Metabolic syndrome (MS) was considered as a disease of adulthood until recently. At present, however, disorders such as obesity, type 2 […]


SGLT2-inhibitors – New Approach in the Treatment of Diabetes

Issue: 4/2014 Author: Kamenov, Zdravko А. Clinic of Endocrinology, “Alexandrovska” University Hospital, Medical University, Sofia     Abstract: Diabetes mellitus (DM) and especially type 2(DM2) became an epidemic, requiring the mobilization of tremendous scientific resource in search of optimal therapeutic approaches aimed at diminishing the personal and social burden of the disease. Being a pathological process in […]


Thyroid Autoimmuniity in Women with Postpartum Thyroid Dysfunction

Issue: 4/2014 Author: Argatska, Antoaneta V.1, Nonchev, Boyan Iv.1, Orbetzova, Мaria М.1, Pehlivanov, Blagovest К.2 1 Clinic of Endocrinology and Metabolic Diseases, 2 Clinic of Obstetrics and Gynaecology, “Sv. Georgy”, University Hospital, Medical University, Plovdiv   Abstract: Autoimmune thyroid diseases (AITD) occur with increased frequency in the postpartum period. Postpartum thyroid dysfunction (PPTD) is the most common […]


The effect of diets with low vs. high glycemic index on plasma levels of leptin and ghrelin in obese patients

Issue: 4/2014 Author: Handjieva-Darlenska, Teodora S.1, Karamfilova, Vera N.2, Kamenov, Zdravko A.2, Boyadjieva, Nadka I.1 1 Department of Pharmacology and Toxicology, Medical Faculty, Medical University, Sofia 2 Clinic of Endocrinology, Alexandrovska hospital, Medical Faculty, Medical University, Sofia   Abstract: The hypothalamus is the main site for regulation of appetite and metabolism. Two major hormones play a role […]


Recommendations for Self-monitoring of Blood Glucose in Diabetes in Central and Eastern Europe

Issue: 4/2014 Author: Tsvetalina Tankova on behalf of the International Central-Eastern European Expert Group* Department of Diabetology, Clinical Center of Endocrinology, Medical University, Sofia * L. Czupryniak (Poland), L. Barkai (Hungary), S. Bolgarska (Ukraine), A. Bronisz (Poland), J. Broz (Check Republic), K. Cypryk (Poland), M. Honka (Check Republic), A. Janez (Slovenia), M. Krnic (Croatia), N. Lalic (Serbia), […]


Thyroid Hormone Resistance Syndrome – a Case Report

Issue: 4/2014 Author: Nonchev, Boyan Iv., Argatska, Antoaneta V., Orbetzova, Maria M. Clinic of Endocrinology and Metabolic Diseases , “Sv. Georgy” University Hospital, Medical University, Plovdiv   Abstract: We describe a case of a 26 year old female with a history of thyroid pathology since the age of 7. In 2007 after a first normal pregnancy and […]


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Journal of the Bulgarian Society of Endocrinology

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