Issue 3/2017

Wnt/Sclerostin and the Regulation of Bone Formation

Issue: 3/2017 Author: Shinkov, Alexander D. Medical University of Sofia, Clinical Centre of Endocrinology and Gerontology Abstract: The regulation of bone metabolism is a complex process that involves the cells in the bone, the bone marrow and a variety of local and systemic humoral factors. The past decade is marked by the accumulation of a large […]


Smoking as a Risk Factor for Insulin Resistance

Issue: 3/2017 Author: Nyagolova, Presiyana V.1, Коleva, Daniela Iv. 1, Orbetzova, Maria M.1, Despotova-Тоleva, Lyubima D.2, Кirov, Lyubomir K. 3 1 – Clinic/Department of Endocrinology and metabolic diseases, “Sv. Georgy” University Hospital, Medical Faculty, Medical University, Plovdiv 2 – Department of Urology and General Medicine, Medical Faculty, Medical University, Plovdiv 3 – Faculty of Medicine, […]


Pleiotropic Effects of the Incretin Hormones and Therapeutic Options

Issue: 3/2017 Author: Stanchev, Pavel E., Orbetzova, Maria M Clinic/Department of Endocrinology and metabolic diseases, “Sveti Georgy” University Hospital, Medical Faculty, Medical University, Plovdiv Abstract: The insulin-like effect in type 2 diabetes mellitus is impaired − glucagon-like peptide-1 (GLP-1) levels are reduced in combination with a reduced response to both incretins − GLP-1 and glucosedependent […]


Gastrointestinal Diseases and Bone

Issue: 3/2017 Author: Temelkova, Natalia L., Popivanov, Plamen R. Department of Clinical densitometry and Bone metabolic diseases, “Aleksandrovska” University Hospital, Sofia Abstract: Regardless of the significant improvement in the diagnosis and treatment of osteoporosis, it remains a socially significant disease with considerable mortality after fractures. Secondary osteoporosis is found in 50-60% of men, 60% of […]


Serum Levels of the Adipocytokines TNF-α и IL-6 in Polycystic Ovary Syndrome

Issue: 3/2017 Author: Koleva, Daniela Iv., Orbetzova, Maria M., Nyagolova, Presiyana V. Clinic/Department of Endocrinology and metabolic diseases, “Sv. Georgy” University Hospital, Medical Faculty, Medical University, Plovdiv Abstract: Visceral adipose tissue (AT) is considered to be a major source of low-grade inflammatory factors in patients with insulin resistance (IR) not only due to the production […]


Prognostic Model for Ultrasound Assessment of Malignancy Risk of Thyroid Nodules

Issue: 3/2017 Author: 1 Nonchev, Boyan Iv., 2 Danev, Vladimir Hr. , 1Argatska, Antoaneta V., 1 Miteva, Maria J., 3 Mateva, Nonka G., 1 Orbetzova, Maria M.Author: Boyadzhieva, Mila B.1 , Hadzhieva, Elitsa G.1 , Hristozov, Kiril H.1 , Georgieva-Hristova, Darina K.2 1 Second Department of Internal Diseases, Clinic/Section of Endocrinology, Faculty of Medicine, Medical University, […]


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Journal of the Bulgarian Society of Endocrinology

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