Issue 2/2019

We compared 46 long-term survivors, aged 9-32 years (mean age 20,6±6,2 y), to 35 age- and sexmatched controls and assessed anthropometric features and biochemical and hormonal parameters. BMD, BMD Z-score, bone mineral content (BMC), fat mass (FM), lean mass (LM) and appendicular muscle mass (AMM) were measured by whole body Dual-energy X-ray absorptiometry (DEXA).

A representative sample of 670 patients, consisting of at least 1 patient from every age interval 0-17 at the time of diagnosis and each calendar year 1975 to 2014 was submitted to the National Agency for Personal Identification. The correct personal data for 614 patients (surviving or deceased) were included in a comparative analysis according to age (0-4, 5-9, 10-17), gender, calendar year of diagnosis ( <1995>), duration of diabetes

Obesity is a chronic and relapsing disease and is becoming more prevalent in younger patients. Latest data suggests that 1,6 billion people worldwide suffer from overweight. Over 400 million people are currently diagnosed with obesity. Treatment of obesity and its comorbidities such as diabetes type 2, arterial hypertension and hypercholesterolemia is a serious burden on the world health system.

Primary hyperparathyroidism (PHPT) was described in the 19th century as a disease of “stones, bones and moans”. The classical clinical picture of PHPT may include different combinations of typical skeletal, renal, gastro-intestinal and neuro-muscular signs and symptoms. The classical forms are known to be a rare disease. With the introduction of serum calcium measurements in the second part of the 20th century hypercalcemia became the landmark of PHPT.