Issue 4/2022

Primary Hyperparathyroidism (PHPT) and Hypoparathyroidism (hypoPT) in Pregnancy and Lactation

Author: Boyanov, Mihail A. Clinic of Endocrinology and Metabolism, University Hospital “Alexandrovska”, Department of Internal Medicine, Medical University, Sofia Abstract: During pregnancy the concentration of 1,25(OH)2 vitamin D increases and the calcium needed by the fetus comes mainly from the gastrointestinal tract. Towards the end of pregnancy, the secretion of PTH-related protein (PTHrP) increases, which ensures […]

Inositol – Its Role in Human Organism and in Development of Some Diseases

Author: Mihaleva, Ivelina D. 1 Medical University of Sofia 2 Kalimat Medical Centre, Sofia Abstract: Inositol is a carbocyclic sugar polyalcohol and is found in many mammalian tissues mediating cellular signal transduction, where it is most often involved as a secondary messenger in response to various hormones, neurotransmitters, growth factors and many other processes. By epimerization […]

The Role of Visceral Adipose Tissue and Skeletal Muscle in the Pathogenesis of Polycystic Ovary Syndrome

Author: Kabakchieva, Plamenа P.1,2, Kamenov, Zdravko A.1 1 Clinic of Endocrinology, Alexandrovska University Hospital, Department of Internal Medicine, Medical University, Sofia 2 Clinic of Internal Diseases, Naval Hospital – Varna, Military Medical Academy, Sofia Резюме: Insulin resistance (IR) and compensatory hyperinsulinemia are among the confirmed pathogenetic mechanisms for the development of polycystic ovary syndrome (PCOS). In […]

Frequency of Obesity / Overweight and Hypertension and Their Relationship with Hyperglycemia among Pregnant Bulgarian Women

Автор: Borissova, Anna-Maria I., Trifonova, Boyana C., Dakovska, Lilia N., Mihailova, Eugenia К, Vukov, Mircho I. Clinic of Endocrinology, “Sofiamed” University Hospital, Faculty of Medicine; Sofia University “St. Kliment Ohridski”, Sofia, Bulgaria Резюме: In Bulgaria, in recent decades, the frequency of Diabetes Mellitus, Obesity or Overweight, Arterial Hypertension, as well as other disease states, was […]

Spontaneous Resolution of Acromegaly with Marked Hypopituitarism – a Case Report

Author: Shishkov, Savi R., Dimitrova, Radina S., Hadzjieva, Elica G., Yaneva, Zhaneta A., Ivanova, Iva V., Siderova, Mira V., Hristozov, Kiril H. Department of Endocrinology and Metabolic Diseases University Hospital “St. Marina”, Medical University, Varna Abstract: Acromegaly is a disease caused by a chronic overproduction of growth hormone. In 95% of cases it is a […]

A Clinical Case of Pheochromocytoma Presenting with Decompensated Diabetes Mellitus and Paroxysmal Hypertension

Author: Markova, Mina M.1, Elenkova, Atanaska P.2,3,Zacharieva, Sabina Z.2, 3 1Medical University, Sofia; 2USHATE “Acad. Ivan Penchev”, Department of Endocrinology, Medical University, Sofia; 3Expert Centre for Rare Endocrine Diseases, Sofia. Резюме: Abstract:   Introduction: Pheochromocytoma is a rare neuroendocrine tumor that originates from the adrenal medulla, less commonly from extraadrenal chromaffin cells (paraganglioma). In about […]

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Journal of the Bulgarian Society of Endocrinology

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