The Nutrional Supplement DIALEVEL Improves Glycaemic Control in Type 2 Diabetic Patients

Issue: 1/2010

Author: D. Koev, L. Koeva

Abstract: 

Experimental studies proved that cinnamon (cinnamomum cassia) and its water extracts contain methylhydroxychalcone polymer (MHPC). It stmulates glucose uptake by muscles and adipocytes by means of an increased insulin sensitivity and besides, it stimulates glycogen synthesis from glucose in the liver. The net result is a decrease of blood glucose. On the other hand, chromium supplementation increases the number of insulin receptors and insulin-receptor binding. This effect also decreases blood glucose. We have studied the clinical effectiveness of a nutritional supplement Dialevel containing water extract of cinnamomum cassia, chromium and alpha-lipoic acid in 30 overweight type 2 diabetic patients with uncontrolled hyperglycemia treated with oral drugs (metformin, sulphonylureas, rosiglithazone or their combinations) on the glycemic control, serum lipids and body weight for 4 months. All patients were controlled monthly and they were not allowed to change their drug treatment and nutritional habits. The nutritional supplement Dialevel was added in 2 or 3 tablets daily according to the individual assessment of the patients. At the end of the observation there was a significant decrease in the mean blood glucose from 8,24 ± 0,79 mmol/l to 6,91 ± 0,41 mmol/l and a decrease in HbA1c from 7,23 ± 0,67 % to 6,34 ± 0,08 %.

Serum lipids and body weight did not change significantly. There were no side effects due to the nutritional supplement. Dialevel may be used successfully in addition to the oral treatment of diabetes mellitus type 2.