Noninsulin dependent diabetes mellitus some genetical aspects
Issue: 1/1998
Author: V. Ivanov, Military Medical Academy – Department of Endocrinology
Abstract:
To establish genetical markers predicting a higher risk for the development of non-insulin dependent diabetes mellitus (NIDDM) we carried out genetic and cytogenetic analysis on a group of 28 NIDDM patients aged 39-60 years. It was found that the percentage of HLA A26 carriers diabetics (17,85%) was three times higher than that of the control group of healthy subjects (6,73%). The diabetic HLA B18, DR1 and DR3 carriers showed twice as large a percentage in comparison to the control group of healthy subjects.
Keywords: NIDDM, gees, antigens, genetical assay, cytogenetical assay.
