Determination of Total Body Water and its Changes during Haemodialysis in Diabetic Patients

Clinical Center of Endocrinology and Gerontology Medical University – Sofia

 

Abstract: 

Determination and attainment of „dry" body weight of normohydration is a principal problem in the treatment of haemodialysis patients. This obtained by extraction of fluids (ultrafiltration) during haemodialysis, associated with extracellular and intracellular volume chan¬ges. The measurement of total body bioelectri-cal impedance in wide frequnce range 200 Hz – 300 kHz gives the information about these processes.

The measurements have been carried out with 34 diabetic patients on longterm dia¬lysis. We established high correlation coefficient between total bioimpedance, calculated total body water (TBW) and realized ultrafiltration -r >  0.9.

We also determined the distribution of extra-   and   intracellular  TBW   as   well   as   the changes   taking   place   in   these   compartments during haemodialisis.

 

Keywords: bioelectrical impedance, impedance spectroscopy, haemodialysis, body fluid balance, diabetes mellitus.